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PRIMROSE: Effect of randomization to neuromuscular blockade on physical functional impairment and recovery in ARDS
June 2016 to May 2020
Multi-center prospective cohort study using stage-appropriate multi-modal assessments of neuromuscular function to determine the effect of randomization to neuromuscular blockers (NMB) in the ROSE trial. The study will assess effect of NMB on the early development of neuromyopathy; on muscle function and strength at hospital discharge; and on physical recovery and healthcare utilization at 6 and 12 months after the development of severe ARDS.